Synerase 90 tabs

Synerase 90 tabs

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Synerase 90 tabs | Bioclinic Naturals

Synerase is a unique proteolytic enzyme combination with diverse clinical benefits, showing efficacy both for digestive function as well as systemic inflammation. This multienzyme formulation contains digestive enzymes with physiological influences extending well beyond protein digestion. This is in part due to the increase in food allergies as a result of incomplete protein digestion, which may be responsible for more systemic effects.1 Beyond protein digestion, bromelain has been shown to reduce blood viscosity, prevent aggregation of blood platelets, reduce levels of prostaglandin E2 and thromboxane A2, and in an open study it improved symptoms of mild, acute knee pain.2,3,4 It also has demonstrated immunomodulatory effects in a variety of models, preventing neutrophil migration in response to IL-8 during inflammation, and inhibiting pro-inflammatory chemokine and cytokine secretion.5,6,7 *
Another component of Synerase, Peptizyme SP, has been evaluated in a number of clinical trials, demonstrating anti-inflammatory, anti-edemic and fibrinolytic properties, resulting in a significant reduction in symptoms for both acute and chronic ear, nose or throat disorders.8 It has also shown antimicrobial properties, modulating proteins involved in bacterial colonization, persistence and invasion.9*
  • Formulated for both anti-inflammatory, antifibrinolytic and immune-modulating activity as well as digestive benefit*
  • Diverse proteolytic activity with a broad range physiological functions and clinical uses extending well beyond protein digestion*
  • Unique, clinically effective, concentrated enzyme formulation, containing pancreatic enzymes, papain, Peptizyme SP and bromelain*
  • Enteric coated tablets*

Synerase 90 tabs | Bioclinic Naturals

Serving Size 2 Tablets 
Servings Per Container 45 

Amount Per Serving 
Pancreatic Enzymes 8x (Sus scrota, pancreas).........................400 mg 
   Amylase activity......................................................80,000 USP units 
   Protease activity......................................................80,000 USP units 
   Lipase activity............................................................6,400 USP units 
Papain (Carica papaya) (latex)..............................................240 mg (7,200,000 USP PU) Peptizyme SPTM Serratia Peptidase (Serratia, whole cell)......104 mg (400,000 SU/g)
Bromelain (Ananas comosus var. comosus) (stem)................100 mg (1,280,000 FCC PU)  

USP (United States Pharmacopoeia), FCC (Food Chemical Codex), PU (Papain Unit), SU (Serratiopeptidase Units) 

Other ingredients: Microcrystalline cellulose, purified water, enteric coating (purified water, ethylcellulose, medium chain triglycerides (coconut), oleic acid, carbohydrate gum [cellulose], glycerin, sodium alginate, stearic acid), maltodextrin, croscarmellose sodium, magnesium stearate (vegetable grade). 

Contains no artificial preservatives, colors or sweeteners; no, dairy, gluten, soy or yeast. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.
1–2 tablets 2 or 3 times per day on an empty stomach. Synerase can also be used for digestive support – take the same dose but with meals.
Consult a health care professional prior to use if you are pregnant or breastfeeding, if symptoms persist or worsen, if you have diabetes, pancreatitis, pancreatic exocrine insufficiency or cystic fibrosis, gastrointestinal lesions/ulcers, are taking anticoagulants/blood thinners, anti-inflammatory agents or other enzyme products, antibiotics, are having surgery, or if you have an allergy to latex or fruits such as avocado, banana, chestnut, passion fruit, fig, melon, mango, kiwi, pineapple, peach and tomato. Hypersensitivity/allergy, nausea, vomiting, abdominal pain/epigastric pain and/or heartburn and diarrhea have been known to occur, in which case discontinue use and consult a health care professional. Keep out of reach of children.
Additional Information
Synerase has fibrinolytic activity, and when taken with antiplatelet or anticoagulant drugs, may increase the risk of bruising and/or bleeding. Bromelain may decrease amoxicillin metabolism.
  1. Untersmayr E, et al. The effect of gastric digestion on food allergy. Curr Opin Allergy Clin Immunol. 2006 Jun;6(3):214-9.
  2. Maurer HR. Bromelain: biochemistry, pharmacology and medical use. Cell Mol Life Sci 2001;58:1234-45.
  3. Juhasz B, et al. Bromelain induces cardioprotection against ischemia-reperfusion injury through Akt/FOXO pathway in rat myocardium. Am J Physiol Heart Circ Physiol. Mar 2008;294(3):H1365-1370.
  4. Walker AF, et al. Bromelain reduces mild acute knee pain and improves well-being in a dose-dependent fashion in an open study of otherwise healthy adults.Phytomedicine 2002 Dec;9(8):681-6.
  5. Fitzhugh, et al. Bromelain treatment decreases neutrophil migration to sites of inflammation. Clin Immunol. Jul 2008;128(1):66-74.
  6. Onken JE, et al. Bromelain treatment decreases secretion of pro-inflammatory cytokines and chemokines by colon biopsies in vitro. Clin Immunol. Mar 2008;126(3):345-352.
  7. Secor ER, et al. Oral Bromelain Attenuates Inflammation in an Ovalbumin-induced Murine Model of Asthma. Evid Based Complement Alternat Med. Mar 2008;5(1):61-69.
  8. Mazzone A, et al. Evaluation of Serratia peptidase in acute or chronic inflammation of otorhinolaryngology pathology: a multicentre, double-blind, randomized trial versus placebo. J Int Med Res. 1990; 18(5):379-88.
  9. Artini M, et al. A new anti-infective strategy to reduce adhesion-mediated virulence in Staphylococcus aureus affecting surface proteins. Int J Immunopathol Pharmacol. 2011 Jul-Sep;24(3):661-72
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*Your results may vary from those listed above.

*These statements have not been evaluated by the Food and Drug Administration.
*This product is not intended to diagnose, treat, cure or prevent any disease.

Since we do not know everything about your medical history and medications, please consult with your health care practitioner before implementing any new protocols and supplements. Do not construe any information listed on this site as a substitute for actual medical advice. The info you receive from us is not intended to replace medical advice by your doctor. Forrest Health, Inc. does not dispense medical advice, prescribe, or diagnose illness. We offer nutritional programs and supplements that support your health. The views and nutritional advice expressed by Forrest Health, Inc. are not intended to be a substitute for conventional medical service. If you have a medical condition, see your physician of choice.