Methylation Support

Methylation Support Supplements

B12 (Methylcobalamin, Hydroxycobalamin, Adenosylcobalamin)
Methyl Folate, 5-MTHF (5-Methyltetrahydrofolic)
SAMe, S-Adenosyl Methionine

The role of the methylation cycle in your body

The methylation cycle is the ideal pathway to focus on for nutritional genetic analysis because the places where mutations occur is well defined and it is clear where supplements can be added to go around these mutations.

The function of the methylation cycle is essential for a number of critical reactions in the body. One consequence of genetic weaknesses (mutations) in this pathway is increased risk factors for a number of serious health conditions. Defects in methylation lay the appropriate groundwork for the further assault of environmental and infectious agents resulting in a wide range of conditions including diabetes, cardiovascular disease, thyroid dysfunction, neurological inflammation, chronic viral infection, neurotransmitter imbalances, atherosclerosis, cancer, aging, schizophrenia, decreased repair of tissue damage, improper immune function, neural tube defects, Down’s syndrome, Multiple Sclerosis, Huntington’s disease, Parkinson’s disease, Alzheimer’s disease, and autism, Inflammation, bacterial, and viral infection

Methylation uses the process of donating ‘Methyl Groups’ to a substrate.

A Methyl Group = 1 Carbon bound to 3 Hydrogens = CH3
Methyl groups substrates are commonly, but not limited to:
- DNA and RNA,
- chemicals,
- Neurotransmitters and hormones,
- immune cells,
- nerves

Functions of Methylation:

Turn on and off genes (gene regulation)
Process chemicals and toxins (biotransformation)
Build neurotransmitters (dopamine, serotonin, epinephrine)
Process hormones (estrogen)
Build immune cells (T cells, NK cells)
DNA and RNA synthesis
Produce energy (CoQ10, carnitine, ATP)
Produce protective myelination coating on nerves

Methylation can be disturbed by:

Lack of cofactors driving methylation forward (zinc, magnesium, B6)
Medications (antacids)
Specific nutrients depleting methyl groups (niacin)
Environmental toxicity, heavy metals, chemicals (acetylaldehyde, arsenic, mercury)
Excessive substrate (feedback inhibition)
Genetic mutations

Signs of methylation issues

Hair	loss, brittle
Brain	anxiety, depression, ADHS, Autism, memory loss, Alzheimer's, insomnia, restless legs, shizophrenia, bipolar disorders
Eyes	teary, redness
Ears	Tinnitus
Thyroid	hypothyroid
Heart	hypotension, strokes, clots
Gut	IBS
Skin	easy bruising, rashes, eczema, vitiligo, psoriasis, poor wound healing, pigmentation
Nails	brittle, ridges
Hormone	low estrogen, testosterone
Energy	fatigue
Allergies	food, celiac
Fertility	neural tube defects, infertility, miscarriages
Muscles	fibromyalgia, muscle pains
Immune	fungus, virus, sinusitis

Genetic SNP Mutations

Many people have mutations in their methylation pathways. Because of this it is necessary to use the 5-MTHF form. If you are not sure, we offer easy to perform genetic tests for methylation.

MTHFR C677T -- 0% loss; +- 40% loss; ++ 70% loss of function
MTHFR A1298C -- 0% loss; +- 20% loss; ++ 40% loss of function

Supplementation

Remember, restarting the mehtylation pathway can start major detoxification of metals, chemicals and viruses. So your mantra should be "Start low, go slow." This means start with low does and slowly increase until you get to the desired dose

It is desirable to help open detoxifcation pathways with homeopathic, botanical and nutraceuticals when up-regulating the methylation pathway. For advise on this you can schedule an appointment with Dr. Forrest.

We off the absolutely highest quality folic acid, Methyltetrahydrofolic acid (5-MTHF), B12 and SAMe supplements from the best companies. We are happy to assist if you need help.

These nutritional supplements are highly suitable for those on the Dr. Amy Yaskow or Rich Van Konyenburg protocols.

Genetic Testing

There are currently a variety of ways to get your testing done. Once the testing is done the results of your methylation pathway must be analyzed to produce an individualized supplement program..

Order your test. Genetic Testing

Understanding MTHFR

Methylation Made Easy Videos

Products

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5-Methyl Folate 1000mcg 90 tabs

SKU: PLFB026

5-Methyl Folate 1000mcg 90 tabs | Protocol For Life Balance - 5-Methyl Folate 1000mcg utilizes a patented form of (read more)

$18.00

Market price: $20.00 save 10%

5-MTHF 1 mg 60 caps

SKU: THRN007

5-MTHF 1 mg 60 caps | Thorne Research - MTHF is an active, tissue-ready form of folate.* It's an essential B vitamin that supports (read more)

$20.00

5-MTHF 120 caps

SKU: PRTY020

5-MTHF 120 caps | Priority One - 5-MTHF is the most biologically active form of folate. Not having enough 5-MTHF can (read more)

$38.99

5-MTHF 15 mg 30 caps

SKU: THRN0071

5-MTHF 15 mg 30 caps | Thorne Research - Active folate supplementation for mood, heart health, fetal development and nerve support.*

$64.98

Market price: $72.20 save 10%

5-MTHF 5 mg 60 caps

SKU: THRN0072

5-MTHF 5 mg 60 caps | Thorne Research - 5-MTHF is an active, tissue-ready form of folate.* It's an essential B vitamin that (read more)

$56.00

Market price: $62.00 save 10%

A Zoom Consultation With Dr. Forrest, DC

SKU: FH001

Zoom Consultation with Dr. Forrest - Dr. Forrest, MA, MH, DC, is a licensed chiropractor in California. His is available for (read more)

$90.00

Acetyl-L-Carnitine 250 mg 60 vcaps

SKU: PURE230

Acetyl-L-Carnitine 250 mg 60 vcaps | Pure Encapsulations - Acetyl-l-Carnitine is a component of the carnitine family (read more)

$37.55

Acetyl-L-Carnitine 500 mg 60 vcaps

SKU: PURE231

Acetyl-L-Carnitine 500 mg 60 vcaps | Pure Encapsulations - Acetyl-l-Carnitine is a component of the carnitine family (read more)

$67.40

Activated B-12 Guard

SKU: PERQ002

Activated B-12 Guard - PERQUE Activated B-12 Guard is in lozenge form for maximum uptake and optimal delivery to the brain. Studies (read more)

$47.25

Market price: $52.50 save 10%

Active B Complex 60 vcaps

SKU: GENT055

Active B Complex 60 vcaps | Genestra - Co-enzymatic vitamin B’s: The body’s natural active form for energy (read more)

$44.65

Active B-Complex 60 vcaps

SKU: INT076

Active B-Complex 60 vcaps | Integrative Therapeutics - Contains Quatrefolic® brand L-Methylfolate, the bioactive (read more)

$18.20

Market price: $20.00 save 9%

Active Bio-B - 60 caps

SKU: EURP014

Active Bio-B - 60 caps | Euromedica - Biologically Active Forms of Vitamin B12 – Folate – B6. Vitamin (read more)

$22.06

Market price: $25.95 save 15%

Active Chew B12 w/L-Methylfolate 60 tabs

SKU: GENT056

Active Chew B12 w/L-Methylfolate 60 tabs | Genestra - Contains 1,000 mcg of methylcobalamin, an active form of vitamin (read more)

$22.15

Market price: $26.20 save 15%

Active Chewable B12 60 tabs

SKU: GENT057

Active Chewable B12 60 tabs | Genestra - Essential vitamin B12 formula in a natural cherry-flavoured chewable. Vitamin (read more)

$19.85

Active Folate 1000 90 vegcaps

SKU: GENT183

Active Folate 1000 90 vegcaps | Genestra - Provides 1000 mcg of folate per day from Metafolin.*

$30.15

Active Folate B12 60 chewable tablets

SKU: DIVN039

Active Folate B12 60 chewable tablets | DaVinci Labs - Active Folate B12 Chewable combines the most active, stable, and (read more)

$28.70

Adenosyl/Hydroxy B12 90 caps

SKU: PURE219

Adenosyl/Hydroxy B12 90 caps | Pure Encapsulations - Adenosyl/Hydroxy B12 offers a unique blend of vitamin B12, as (read more)

$25.80

AdreCor with SAMe 30 vcaps

SKU: NS046

AdreCor with SAMe 30 vcaps | NeuroScience - Contains non-glandular ingredients important for adrenal health and mood.*

$66.00

Advanced Methyl Detox Profile

SKU: ALCT007

Advanced Methyl Detox Profile | Cell Science Systems - The Methyl Detox Profile expands on MTHFR genotyping, giving (read more)

$399.00

B-Complex +10 mg L-Methylfolate 30 caps

SKU: METHP010

B-Complex +10 mg L-Methylfolate 30 caps | MethyPro - Our B-Complex products combine our best-selling phosphorylated B-Complex (read more)

$40.50

Market price: $54.00 save 25%

Reviews

IntraMax Liquid Vitamin

I have been using intraMAX and the results have been excellent. I continue to have substantial improvement in the quality of my life. I also have not had a cold or the flu in almost four years. Mel Renfro Former Dallas Cowboy and NFL Hall of Famer Thank you, Dr. Drucker, for developing an outstanding whole foods nutritional product. I've been taking intraMAX now for over 8 months along with several other family members. The results have been outstanding for all of us. For the past 25 plus years I've personally been involved in whole foods nutritional support and never before have I witnessed the positive results from taking intraMAX. The best part has been that it's easy to take and you know you're getting everything you need in one easy capful. Thank you again and I couldn't imagine not having my daily dose of intraMAX. Karen Klatt I consider intraMAX the quintessential liquid nutritional supplement. Besides being great tasting, it gives each of my patients a...

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Jun 1, 2019

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