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Methylation Support
Methylation Support Supplements
- B12 (Methylcobalamin, Hydroxycobalamin, Adenosylcobalamin)
- Methyl Folate, 5-MTHF (5-Methyltetrahydrofolic)
- SAMe, S-Adenosyl Methionine
Methylation uses the process of donating ‘Methyl Groups’ to a substrate.
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A Methyl Group = 1 Carbon bound to 3 Hydrogens = CH3
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Methyl groups substrates are commonly, but not limited to:
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DNA and RNA,
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chemicals,
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Neurotransmitters and hormones,
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immune cells,
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nerves
Functions of Methylation:
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Turn on and off genes (gene regulation)
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Process chemicals and toxins (biotransformation)
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Build neurotransmitters (dopamine, serotonin, epinephrine)
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Process hormones (estrogen)
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Build immune cells (T cells, NK cells)
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DNA and RNA synthesis
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Produce energy (CoQ10, carnitine, ATP)
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Produce protective myelination coating on nerves
Methylation can be disturbed by:
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Lack of cofactors driving methylation forward (zinc, magnesium, B6)
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Medications (antacids)
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Specific nutrients depleting methyl groups (niacin)
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Environmental toxicity, heavy metals, chemicals (acetylaldehyde, arsenic, mercury)
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Excessive substrate (feedback inhibition)
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Genetic mutations
Signs of methylation issues
| Hair | loss, brittle |
| Brain | anxiety, depression, ADHS, Autism, memory loss, Alzheimer's, insomnia, restless legs, shizophrenia, bipolar disorders |
| Eyes | teary, redness |
| Ears | Tinnitus |
| Thyroid | hypothyroid |
| Heart | hypotension, strokes, clots |
| Gut | IBS |
| Skin | easy bruising, rashes, eczema, vitiligo, psoriasis, poor wound healing, pigmentation |
| Nails | brittle, ridges |
| Hormone | low estrogen, testosterone |
| Energy | fatigue |
| Allergies | food, celiac |
| Fertility | neural tube defects, infertility, miscarriages |
| Muscles | fibromyalgia, muscle pains |
| Immune | fungus, virus, sinusitis |
Genetic SNP Mutations
Many people have mutations in their methylation pathways. Because of this it is necessary to use the 5-MTHF form. If you are not sure, we offer easy to perform genetic tests for methylation.
- MTHFR C677T -- 0% loss; +- 40% loss; ++ 70% loss of function
- MTHFR A1298C -- 0% loss; +- 20% loss; ++ 40% loss of function
Supplementation
Remember, restarting the mehtylation pathway can start major detoxification of metals, chemicals and viruses. So your mantra should be "Start low, go slow." This means start with low does and slowly increase until you get to the desired dose
It is desirable to help open detoxifcation pathways with homeopathic, botanical and nutraceuticals when up-regulating the methylation pathway. For advise on this you can schedule an appointment with Dr. Forrest.
We off the absolutely highest quality folic acid, Methyltetrahydrofolic acid (5-MTHF), B12 and SAMe supplements from the best companies. We are happy to assist if you need help.
These nutritional supplements are highly suitable for those on the Dr. Amy Yaskow or Rich Van Konyenburg protocols.
Genetic Testing
There are currently a variety of ways to get your testing done. Once the testing is done the results of your methylation pathway must be analyzed to produce an individualized supplement program..
- Order your test. Genetic Testing
Understanding MTHFR
Methylation Made Easy Videos
Products
5-MTHF 15 mg 30 caps | Thorne Research - Active folate supplementation for mood, heart health, fetal development and nerve support.*
Active Folate 1000 90 vegcaps | Genestra - Provides 1000 mcg of folate per day from Metafolin.*
AdreCor with SAMe 30 vcaps | NeuroScience - Contains non-glandular ingredients important for adrenal health and mood.*
Reviews
Bestsellers
- ReadiSorb Methyl B12 Spray
- L-Methylfolate 10 mg from Quatrefolic 30 caps
- L-Methylfolate 15mg +Cofactors 30 caps
- Consultation With Dr. Forrest, DC
- L-Methylfolate 10mg + Cofactors 30 caps
- Methyl Care 120 caps
- L-Methylfolate 15 mg 60 Caps
- Vitamin B12 Liquid Methylcobalamin 1mg 4oz
- B12-ND 2 oz
- L-Methylfolate 5 mg 90 Caps
Related Entries
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10/04/2011
Neo40 Professional Nitric Oxide Booster
- Neo 40 helps improve circulation and the cardiovascular system
- NEO 40 raises Nitric Oxide
- ED is caused by low Nitric Oxide
- Now available in 60 lozenges
- NEW Proessional Strength version available
| Price: | $119.89 |
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