Pure NAD+ Micromist Nasal Spray – Nicotinamide Adenine Dinucleotide

Pure NAD+ Micromist Nasal Spray – Nicotinamide Adenine Dinucleotide

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SKU
ALIVE009
Quantity in stock
1000 item(s)
Modified
4/21
Size
1 oz
Supplier
ALIVE
MPN
PNADM
UPC
656165996483
Our Price:
$44.95
 
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Pure NAD+ MICROMIST Nasal Spray – Nicotinamide Adenine Dinucleotide | Alive By Science

Intranasal delivery is the quickest, most efficient way to deliver NAD+ directly to the brain. It is the best option to bypass the blood-brain barrier, reduce systemic adverse effects of drugs, and to allow a lower dose of drugs to be administered.*

  • 3 grams NAD+ per bottle
  • 2 sprays deliver approximately 25 mg NAD+
  • Pharmaceutical grade
  • Naturally stabilized
  • 3rd party tested for purity and safety

Intranasal delivery bypasses the GI tract and delivers NAD+ directly to the bloodstream.

Intranasal delivery of NAD+

Intranasal delivery is the quickest, most efficient way to deliver NAD+ directly to the brain. It is the best option to bypass the blood-brain barrier, reduce systemic adverse effects of drugs, and to allow a lower dose of drugs to be administered.

Intranasal delivery bypasses the blood/brain barrier

 

The purpose of the blood–brain barrier is to protect against toxins or pathogens circulating in the blood that might cause brain infections, while at the same time allowing vital nutrients to reach the brain.

In a study published in September 2018, administration of LABELED NAD+ by IP and IV injection demonstrated that exogenous NAD+ crosses the blood brain barrier to enter the hypothalamus INTACT, reduces hunger and weight gain, and increases energy expenditure and fat burning in mice.

The study also shows that NR and NMN can not utilize the cd43 gap to cross the blood brain barrier.

"In conclusion, our results demonstrate that exogenous NAD is effectively imported into the hypothalamus and increases hypothalamic NAD content. Therefore, NAD supplement can constitute a therapeutic method for metabolic disorders characterized by hypothalamic NAD depletion in humans."(1)

Intranasal reduces systemic adverse effects of drugs

Because intranasal delivers drugs to a targeted area, it reduces the chances for systemic adverse side effects.  Systemic side effects are defined as those effects occurring in tissues distant from the site of contact between the body and the medical device or biomaterial.

"Furthermore, the drugs administered using nasal route have usually higher bioavailability, less side effects and result in higher brain exposure at similar dosage than the oral drugs."(2)

Intranasal Delivery - The so-called nose-to-brain pathway

 

Studies in mice show that intranasally-administered NAD+ increase hippocampal NAD+ levels and reduce TBI-induced neuronal death in the hippocampus. 

"The profound protective effects of the intranasal NAD+ administration were also observed at 72 hrs after ischemia."*

"intranasal administration with 10 mg / kg NAD+, but not with 5 mg / kg NAD+, significantly attenuated the ischemia / reperfusion-produced neurological deficits"*

Loss of blood flow due to traumatic brain injury or stroke also results in NAD+ starvation and neuronal death.

 

 

Pure NAD+ MICROMIST Nasal Spray | Alive By Science

  • 3 grams NAD+ per bottle
  • 2 sprays deliver approximately 25 mg NAD+
  • Pharmaceutical grade

 

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  • Disclaimer

*Your results may vary from those listed above.

*These statements have not been evaluated by the Food and Drug Administration.
*This product is not intended to diagnose, treat, cure or prevent any disease.

Since we do not know everything about your medical history and medications, please consult with your health care practitioner before implementing any new protocols and supplements. Do not construe any information listed on this site as a substitute for actual medical advice. The info you receive from us is not intended to replace medical advice by your doctor. Forrest Health, Inc. does not dispense medical advice, prescribe, or diagnose illness. We offer nutritional programs and supplements that support your health. The views and nutritional advice expressed by Forrest Health, Inc. are not intended to be a substitute for conventional medical service. If you have a medical condition, see your physician of choice.