ReadiSorb Liposomal Glutathione
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ReadiSorb Liposomal Glutathione
One teaspoon contains over 420 mg of easily absorbed reduced l-glutathione.
Glutathione (GSH), a naturally occurring protein, is called a peptide. It is composed of three amino acids: glycine, glutamine and cysteine. Cysteine contains sulfur and gives glutathione its sulfuric aroma. It also plays a major role in glutathione’s antioxidant and detoxification functions.
Glutathione functions to:
- Protect cells against free radicals that cause oxidation damage
- Neutralize/remove toxins
- Enhance immune function
- Regulate protein and DNA growth
Glutathione, with its anti-inflammatory properties, is considered a “key antioxidant” in the functioning of cells. Antioxidant means it helps prevent oxidative stress.
Oxidation in the outside world is the chemical mechanism that causes rust. Inside the body oxidation damage, called oxidative stress, causes damage to the proteins that keep the cells and their membranes running. Oxidative stress refers to toxins produced inside the body, free radicals, and those from without, which are caused by the environment. Glutathione plays a critical role in defending cells again oxidative stress.
Glutathione deficiency contributes to oxidative stress, which plays a key role in aging and the pathogenesis of many diseases including kwashiorkor, seizure, Alzheimer’s disease, Parkinson’s disease, liver disease, cystic fibrosis, sickle cell anemia, HIV, AIDS, cancer, heart attack, stroke, and diabetes.(1)
Cystic Fibrosis & Lung Disease
In cystic fibrosis, lung disease is typified by an inflammatory response. This leads to oxidative stress in the lungs. Glutathione is the primary intracellular antioxidant, and provides an important defense in the epithelial lining fluid. (2)
“… GSH system dysfunction may be the trigger for initial depletion of other antioxidants and may also play a role in initiating the over-inflammation characteristic of cystic fibrosis. Proper GSH system functioning also affects immune system competence and mucus viscosity, both of relevance to cystic fibrosis pathophysiology. In a way, cystic fibrosis may be thought of as the first identified disease with GSH system dysfunction”. (3)
Glutathione is present in the epithelial lining fluid of the normal lower respiratory tract, where it is thought to play a major role in providing antioxidant protection to the epithelial cells. A study done on patients with IDP (idiopathic pulmonary fibrosis) showed the lower respiratory tracts to be chronically depleted of glutathione. (4)
Rational, integrative management of Parkinson’s disease requires, among other things, aggressive repletion of glutathione. (5)
There is a reduction in the levels of reduced glutathione in … Lewy body disease (presymptomatic Parkinson’s disease) of the same magnitude as occurs in advanced Parkinson's disease. This would suggest that alterations in glutathione function are an early marker of pathology in Parkinson's disease… (6)
In one study it was shown that the concentration of glutathione was decreased in red blood cells from male Alzheimer’s disease patients compared with age- and gender-matched controls. (7)
A study of asthmatic children found a correspondence between the level of glutathione and the severity of asthma attack. Lowest levels of glutathione were found during acute asthmatic attacks. (8)
Glutathione is essential for the viability and function of virtually all cells. In vitro studies showing that low GSH levels both promote HIV expression and impair T cell function suggested a link between GSH depletion and HIV disease progression. (9)
This study looked at the metabolism of autistic children. Impairments in the methylation cycle, a very critical part of our body’s functioning, were found. Because of this problem in the methylation cycle, autistic children are predisposed to low glutathione which prevents them from detoxifying normally. It was also found that certain co-enzymes, all non-pharmaceutical, support that cycle. (10)
(1) Guoyao, Wu et al Glutathione metabolism and its implications for health J Nutr. 2004 Mar; 134(3):489-92.
(2) Lands, L et al. Lymphocyte Glutathione Levels in Children With Cystic Fibrosis. Chest. 1999; 116:201-205.
(3) Hudson, VM New insights into the pathogenesis of cystic fibrosis: pivotal role of glutathione system dysfunction and implications for therapy. Treat Respir Med. 2004; 3(6):353-63.
(4) Cantin AM et al Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis. Am Rev Respir Dis. 1989 Feb; 139(2):370-2.
(5) Kidd PM Parkinson's disease as multifactorial oxidative neurodegeneration: implications for integrative management. Altern Med Rev. 2000 Dec; 5(6):502-29.
(6) Jenner P Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease. Acta Neurol Scand Suppl. 1993; 146:6-13.
(7) Liu H, et al Gender differences in glutathione metabolism in Alzheimer's disease J Neurosci Res. 2005 Mar 15;79(6):861-7.
(8) Bibi H et al. Erythrocyte glutathione peroxidase activity in asthmatic children. Ann Allergy. 1988 Nov; 61(5):339-40.
(9) Herzenberg, LA et al Glutathione deficiency is associated with impaired survival in HIV disease Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1967-72.
(10) James, SJ et al Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.
Am J Clin Nutr. 2004 Dec; 80(6):1611-7.
For an alternative liposomal glutathione product without a password.
ReadiSorb Liposomal Glutathione Reduced l-glutathione Purified water Lecithin – The liposomes in ReadiSorb Glutathione are derived from lecithin. The lecithin is derived from oil extracted from soy, so there is a low, but potential, chance of immune reaction to this product. Glycerin – Also known as glycerol, glycerin is used as a sweetener and as a preservative. Glycerol is a normal product of fat metabolism and is readily converted to glucose for metabolism. The glycerin used in this product is derived from a vegetable source. It supports the stability of the liposomes and allows for the extended shelf life. Potassium Sorbate – A natural material used as a preservative to prevent yeast and mold growth. It is a form of sorbic acid, a naturally occurring fatty acid which is easily metabolized in the body. Potassium sorbate is used to preserve wine, baked goods and cheese. Directions for use: Shake bottle. Take straight or mix with water or juice. Recommended adult starting dose is 1 teaspoon. Children: 1/8 – 1/4 teaspoon for every 30 lb of weight. Take in the morning on an empty stomach. This product is approved for use on the Feingold Program. This product requires a password to purchase. It is meant to be used under doctor's supervision. For an alternative liposomal glutathione product without a password. Click the link below. LipoCeutical Glutathione
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