The Organix Profile
Chronically Ill Patients Want an Answer, Not a Label

Identifying the cause of chronic illness is the first step toward achieving a favorable outcome. Integrative clinicians rely on the Organix Profile by Metametrix to reveal the nutritional and metabolic basis of patient symptoms, just as traditional practitioners might use a serum chemistry to establish a diagnostic baseline.

The Organix Profile provides a view into the body and its cellular metabolic processes and the efficiency of metabolic function. Identifying metabolic blocks that can be treated nutritionally allows individual tailoring of interventions that maximize patient responses and lead to improved patient outcomes.

Organic acids are metabolic intermediates produced in pathways of central energy production, detoxification, neurotransmitter breakdown, or intestinal microbial activity. Accumulation of specific organic acids in urine often signals a metabolic inhibition or block. This may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or drug effect.

From a single urine specimen, the Organix Profile by Metametrix provides important information in the areas of:

• Vitamin and mineral insufficiencies
• Amino acid insufficiencies like carnitine and NAC
• Oxidative damage and anti-oxidant sufficiency markers
• Indicators to assess detoxification sufficiency
• The best functional markers of B-complex deficiency
• Neurotransmitter metabolites to assess CNS function
• Mitochondrial energy production assessment via citric acid cycle components
• Methylation sufficiency status
• Lipoic acid and CoQ10 sufficiency markers
• Specific dysbiosis markers for bacterial and yeast overgrowth

Why is Measuring Organic Acids Important ?
Conditions ranging from rapid aging and "brain fog" to siezure disorders are being corrected when underling causes are revealed by Organix testing.

Your body is constantly generating products from metabolic reactions. Modern technology allows the accurate measurement of these metabolic products in urine. Many of the compounds that are found give clues about how your body is working and where specific additions of vitamins or minerals may be needed. For example, scientific research has shown that a deficiency of vitamin B12 produces high levels of a urinary organic acid called methylmalonic acid. Other organic acids can show deficiencies of vitamin B1, vitamin B6, or folic acid. This profile measures many such compounds that let us see evidence of your need for virtually all B-vitamins. Also included are organic acids produced by intestinal bacteria and yeasts as well as products of hormones and detoxification.

An Important Test for Chronic Illness
Many chronic health problems can be difficult to diagnose, especially when they involve nonspecific symptoms such as fatigue, foggy thinking, malaise, gastrointestinal upset, joint aches,or sleep cycle disturbances. Standard medical tests are designed to identify disease states. Organic acid testing does not diagnose disease; it helps to give insight into the causes of disease. This profile helps us assess specific metabolic dysfunctions. Then we can customize a nutritional program for you that manages those areas in need of support. This allows an approach that is beyond symptom management. Our goal is to identify dysfunctions related to nutritional deficiencies and correct them before disease is allowed to develop.

Conditions that doctors may use Organix for include:

• Developmental Disorders
• Obesity
• Depression/Anxiety
• Siezure
• Chronic Fatigue
• Genetic Tendencies
• Diabetes
• Heart Disease
• Cancer
• Alzheimer's disease
• Toxic Exposure
• Inflammatory bowel diseases
• Diarrhea

Why Do We Use the Organix Profile?
Metametrix was the first clinical laboratory to offer quantitative organic acid profiling. Their ongoing research continually raises the standard for urine organic acid analysis. Metametrix methods accurately and reliably measure the tiny quantities of metabolic intermediates in a urine sample.

Not Certain What To Do Next?
If you are uncertain as to which products or programs to use or which tests to take; or, if you would like additional help:

• Contact us with a brief question.
• Arrange a phone consultation with Dr. Forrest.
  Call ( 408) 354-4262

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