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Ayur-Gymnema 60 caps | Douglas Labs Glucose metabolism that is associated with abnormally high blood glucose can lead to high levels of glycation. Glycation is the non-enzymatic attachment of sugars to major molecules in the body, including proteins, lipids, and nucleic acids. Glycation reactions generate advanced glycation end-products (AGEs) and glycotoxin intermediates. AGEs cause abnormal and destructive functioning of body proteins, lipids, and nucleic acids. AGE-associated damage is suspected in the pathogenesis of many diseases and age-related deteriorations, such as atherosclerosis, Alzheimer’s disease, and severe diabetic complications, including neuropathy, nephropathy, retinopathy, and cataracts. Gymnema sylvestre is an Ayurvedic botanical that may assist in the regeneration and repair of pancreatic beta cells. Gymnema is also suspected of reducing intestinal glucose absorption. Native to India, this woody, climbing plant has been used traditionally in India to treat madhu meha, or “honey urine.” Gymnemic acid, an active component of Gynema sylvestre, has been identified in numerous animal studies as having anti- hyperglycemic effects. Human studies in both type I and type II diabetics have shown to decrease blood sugar and subsequently, a decrease in the patients’ requirements for medication.
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