Optimized Folate 1000mcg 100 vcaps

Optimized Folate 1000mcg 100 vcaps
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Optimized Folate 1000mcg 100 vcaps | Life Extension Foundation

Folate is involved in neurotransmitter synthesis and critical enzymatic reactions throughout the body. By depleting excess homocysteine, folate benefits cardiovascular health and nervous system function.

Optimal levels of folate are necessary for healthy cell division and protein synthesis and are especially important for the maintenance of a healthy GI tract. The systemic need for folate increases in certain states in which increased cell multiplication is needed. Chronic use of medications such as aspirin in therapeutic doses and antacids can interfere with the metabolism of folate.178

Those who take ordinary folate supplements, however, may not be experiencing its full spectrum of effects. This is because once ingested, not everyone converts folate to its biologically active form called 5-methyltetrahydrofolate (5-MTHF).180 Research shows that in a large proportion of the population, genetic enzyme deficiencies prevent the conversion of folate to 5-MTHF, leaving many vulnerable to low blood folate levels (and higher than desired homocysteine).

A more useful approach is to take the bioactive folate 5-MTHF directly, which has been declassified as a drug and is now available as a dietary supplement. 5-MTHF has been shown to dramatically raise red blood cell folate concentration, an indicator of folate status181 compared with folic acid supplementation. This bioactive folate is up to seven times more bioavailable than folic acid. This greater bioavailability is especially important in people who have a genetic enzyme deficiency182since it requires no conversion to become metabolically active.

A study of 10 patients with endothelial dysfunction showed complete reversal of endothelial impairment after 5-MTHF supplementation compared with healthy control patients.183

People with elevated homocysteine levels have a greater risk of cognitive decline.184 Unlike folic acid, 5-MTHF is able to cross the blood-brain barrier, which is especially important for people with cognitive difficulties to enhance the synthesis of acetylcholine in the brain — the neurotransmitter associated with memory.

Studies also show that the effectiveness of 5-MTHF can be further enhanced by co-supplementing with methylcobalamin (the active form of vitamin B12),185 vitamin B6, and riboflavin

Optimized Folate 1000mcg 100 vcaps | Life Extension Foundation

Optimized Folate 1000mcg 100vcaps

Dietary Supplement

Read the entire label and follow the directions carefully prior to use.

DIRECTIONS: Take one (1) capsule daily with food, or as recommended by a healthcare practitioner.

Supplement Facts
Serving Size 1 Vegetarian Capsule
Amount Per Serving
Folate 1000 mcg
[as (6S)-5-Methyltetrahydrofolic acid,
glucosamine salt]^
Other ingredients: microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.

This product contains NO milk, egg, fish, peanuts, crustacean shellfish (lobster, crab, shrimp), soybeans, tree nuts, wheat, yeast, gluten, corn, or rice. Contains NO sugar, and no artificial sweeteners, flavors, colors, or preservatives.

Store tightly closed in a cool, dry place.

WARNINGS:
• KEEP OUT OF REACH OF CHILDREN.
• DO NOT EXCEED RECOMMENDED DOSE.
• Do not purchase if outer seal is broken or damaged.
• When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat,
cure, or prevent any disease.

^Quatrefolic® is a registered trademark of Gnosis S.p.A.

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Disclaimer: The statements enclosed herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease

Since we do not know everything about your medical history and medications, please consult with your health care practitioner before implementing any new protocols and supplements. Do not construe any information listed on this site as a substitute for actual medical advice. The info you receive from us is not intended to replace medical advice by your doctor. Forrest Health, Inc. does not dispense medical advice, prescribe, or diagnose illness. We offer nutritional programs and supplements that support your health. The views and nutritional advice expressed by Forrest Health, Inc. are not intended to be a substitute for conventional medical service. If you have a medical condition, see your physician of choice

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