Methylation Support Supplements
- B12 (Methylcobalamin, Hydroxycobalamin, Adenosylcobalamin)
- Methyl Folate, 5-MTHF (5-Methyltetrahydrofolic)
- SAMe, S-Adenosyl Methionine
Methylation uses the process of donating ‘Methyl Groups’ to a substrate.
A Methyl Group = 1 Carbon bound to 3 Hydrogens = CH3
Methyl groups substrates are commonly, but not limited to:
DNA and RNA,
Neurotransmitters and hormones,
Functions of Methylation:
Turn on and off genes (gene regulation)
Process chemicals and toxins (biotransformation)
Build neurotransmitters (dopamine, serotonin, epinephrine)
Process hormones (estrogen)
Build immune cells (T cells, NK cells)
DNA and RNA synthesis
Produce energy (CoQ10, carnitine, ATP)
Produce protective myelination coating on nerves
Methylation can be disturbed by:
Lack of cofactors driving methylation forward (zinc, magnesium, B6)
Specific nutrients depleting methyl groups (niacin)
Environmental toxicity, heavy metals, chemicals (acetylaldehyde, arsenic, mercury)
Excessive substrate (feedback inhibition)
Signs of methylation issues
|Brain||anxiety, depression, ADHS, Autism, memory loss, Alzheimer's, insomnia, restless legs, shizophrenia, bipolar disorders|
|Heart||hypotension, strokes, clots|
|Skin||easy bruising, rashes, eczema, vitiligo, psoriasis, poor wound healing, pigmentation|
|Hormone||low estrogen, testosterone|
|Fertility||neural tube defects, infertility, miscarriages|
|Muscles||fibromyalgia, muscle pains|
|Immune||fungus, virus, sinusitis|
Genetic SNP Mutations
Many people have mutations in their methylation pathways. Because of this it is necessary to use the 5-MTHF form. If you are not sure, we offer easy to perform genetic tests for methylation.
- MTHFR C677T -- 0% loss; +- 40% loss; ++ 70% loss of function
- MTHFR A1298C -- 0% loss; +- 20% loss; ++ 40% loss of function
Remember, restarting the mehtylation pathway can start major detoxification of metals, chemicals and viruses. So your mantra should be "Start low, go slow." This means start with low does and slowly increase until you get to the desired dose
It is desirable to help open detoxifcation pathways with homeopathic, botanical and nutraceuticals when up-regulating the methylation pathway. For advise on this you can schedule an appointment with Dr. Forrest.
We off the absolutely highest quality folic acid, Methyltetrahydrofolic acid (5-MTHF), B12 and SAMe supplements from the best companies. We are happy to assist if you need help.
These nutritional supplements are highly suitable for those on the Dr. Amy Yaskow or Rich Van Konyenburg protocols.
There are currently a variety of ways to get your testing done. Once the testing is done the results of your methylation pathway must be analyzed to produce an individualized supplement program..
- Order your test. Genetic Testing
Methylation Made Easy Videos
AdreCor with SAMe 30 vcaps | NeuroScience - Adrenal support* Supports healthy adrenal function to help maintain energy levels and manage stress(hide)
Advanced Methyl Detox Profile | Cell Science Systems - The Methyl Detox Profile expands on MTHFR genotyping, giving you a more complete picture of your body’s detoxification abilities(hide)
B12 Adenosylcobalamin 60 loz | Allergy Research Group - Coenzyme vitamin B12 in the form of adenosylcobalamin, also known as dibencozide. This is the active form of vitamin B12 used by the mitochondria, the energy powerhouse in each cell.* 3000 mcg Adenosylcobalamin with Folic Acid(hide)
B12 Liposomal Spray 2 oz | Vinco - Methylcobalamin & Hydroxycobalamin forms with Methyl Folate and Trimethylglycine in highly absorbable liposomes.(hide)
Methylcobalamin B12 liquid 30 ml | Pure Encapsulations Methylcobalamin liquid for nerve health and cognitive function. Methylcobalamin (B12) 1000 mcg(hide)
B12 Methylcobalamin 1000 mcg 60 loz | Bioclinic Naturals - Methylcobalamin Biologically Active Form 1000 mcg. Vitamin B-12 (as methylcobalamin) 1,000 mcg(hide)
B12 Methylcobalamin 50 Lozenges | Allergy Research Group - Coenzyme vitamin B12 in the form of methylcobalamin, with folic acid. 3000 µg Methylcobalamin with Folic Acid(hide)
B12 Methylcobalamin 5000 mcg 60 loz | Bioclinic Naturals - Methylcobalamin Biologically Active Form 5000 mcg
B12-ND 2 oz | Premier Research Labs - rich, live source of vitamin B12 in preferred probiotic-cultured forms. Vitamin B12 supports nervous system health and the formation of blood, fatty acids and nucleic acids.
Basic Methyl Detox | Cell Science Systems - The Methyl Detox Profile expands on MTHFR genotyping, giving you a more complete picture of your body’s detoxification abilities(hide)
Consultation with Dr. Forrest - Dr. Forrest, MA, MH, DC, is a licensed chiropractor in California. His is available for in-office visits and informational/educational phone/Skype consultations and Zyto and EVOX Biometric Body Scans. You are welcome to draw on his over 28 years of clinical experience.(hide)
Curcum-Evail 60 softgels | Designs for Health - three curcuminoids are the strongest, most protective and best researched constituents of the turmeric root(hide)
Folate 1000 90 vcaps | Pure Encapsulations | Pure Encapsulations - L-5-methyltetrahydrofolate (L-5-MTHF), the naturally occurring, universally metabolized form of folate.
High Potency Optimized Folate 30 vegtabs | Life Extension Foundation - biologically active form, 5-methyltetrahydrofolate, or 5-MTHF.(hide)
Homocysteine Response 90 tablets | Innate Response Formulas - clinical potencies of vitamin B6, folate and B12. These three nutrients are required for the conversion of homocysteine.
Homocysteine Support 60 vegcaps | Genestra - provides a combination of betaine and physiologically active B vitamins to help support healthy homocysteine levels(hide)
L-5-MTHF 120 capsules | Designs for Health - High dose, 1000 mcg methylated folate, as the natural 6S isomer
Liposomal B12/Methylfolate 2 fl oz | Empirical Labs - High Quality Liposomal Vitamin B12 and Methylfolate Containing 500 mcg Vitamin B12,(hide)
Magnesium Bisglycinate 90 caps | Vinco - Magnesium Bisglycinate Chelate Buffered is a highly absorbed form of magnesium and is gentle on the stomach(hide)
Magnesium Chelate 120 | Designs for Health - Magnesium bisglycinate chelate is one of the best absorbed forms of magnesium
Neo40 Professional Nitric Oxide Booster
- • Neo 40 helps improve circulation and the cardiovascular system
- • NEO 40 raises Nitric Oxide
- • ED is caused by low Nitric Oxide
- • Now available in 30 or 60 lozenges
- • NEW Proessional Strength version available
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