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Hepagen-Fc 60 vcaps | Thorne Vet

Hepatic support for cats and small dogs

  • protects hepatic cells
  • supports normal phase I and II detoxification processes
  • supports healthy glutathione levels

Because toxic components increasingly find their way into food, water, and the environment, the liver can be a very busy organ for companion animals. Hepagen-Fc provides a unique combination of the beneficial liver herbs milk thistle and curcumin (from turmeric), with antioxidants and important ingredients that support the liver's normal phase I and phase II detoxification processes. Hepagen-Fc contains the curcumin phytosome, CurcuVET®, a unique, well-absorbed curcumin/phosphatidylcholine complex.

Whether taken from food or as a supplement, curcumin is generally poorly absorbed into the bloodstream. Indena S.p.A., the worldwide experts in botanical extract technology, has uncovered the key to curcumin absorption – phytosome technology. CurcuVET is Indena?s unique curcumin extract that is significantly better absorbed than other curcumin extracts. The beneficial effects of curcumin may be due to the fact that, in addition to being a potent antioxidant, it can help maintain the animal's normal inflammatory response.

Silybum marianum (milk thistle) contains several flavonolignans, the most potent of which is silybin. The antioxidant activity of silybin appears to stabilize hepatocyte membranes, neutralize free radicals, and maintain the liver's glutathione levels. Hepagen-Fc contains silybin in the form of a well-absorbed phytosome bound to phosphatidylcholine (Siliphos®).

The phosphatidylcholine content of CurcuVET and Siliphos – in addition to enhancing the absorption of these important hepatoprotective flavonoids – also provides liver support in its own right. Phosphatidylcholine is the most significant phospholipid in hepatic cell membranes. It helps regulate the gallbladder and is used extensively in the liver to move fats in and out of cells.

Pyridoxal 5'-phosphate acts as a cofactor for enzymes, catalyzes reactions with amino acids, and aids in the synthesis of non-essential amino acids. In this formula, the active form of vitamin B6, pyridoxal 5'-phosphate, is provided because healthy liver function is necessary for activation of vitamin B6. Vitamin B12 is required for proper digestion and absorption of food and is provided in one of its active coenzyme forms – methylcobalamin.

Dimethylglycine (DMG) is a derivative of glycine, the simplest amino acid. It is a building block for many important substances, including methionine and choline. Methionine is an essential sulfur-containing amino acid necessary for phase II detoxification. It helps metabolize fats and is a precursor to cysteine and taurine synthesis. It can be converted to cysteine, a component of glutathione, an important endogenous antioxidant.

N-acetylcysteine (NAC) is composed of the amino acid cysteine and a sulfhydryl group, enabling it to interact with disulfide bonds. NAC serves as a precursor for the synthesis of glutathione.

Inositol is an important lipotropic factor – a substance that helps the liver metabolize fats.


Hepagen-Fc 60 vcaps | Thorne Vet

Active Ingredients per Capsule:
L-Methionine 22.5 mg.
N-Acetyl-L-Cysteine 22.5 mg.
Dimethylglycine (Hydrochloride) 11.3 mg.
Inositol 11.3 mg.
Milk Thistle Phytosome* (Silybum marianum extract (seed) / Phosphatidylcholine complex) (Siliphos®) 11.3 mg.
Curcumin Phytosome* (Curcuma longa extract (root) / Phosphatidylcholine complex) (CurcuVET®) 11.3 mg.
Pyridoxal 5'-Phosphate (Vitamin B6) 1.3 mg.
Methylcobalamin (Vitamin B12) 12.5 mcg.
Inactive Ingredients: Hypromellose (derived from cellulose) capsule, Leucine, Microcrystalline Cellulose, Natural Bacon Flavoring, Silicon Dioxide.

*This product uses Indena S.p.A.'s curcumin phytosome (CurcuVET®) and silybin phytosome (Siliphos®). CurcuVET and Siliphos are registered trademarks of Indena S.p.A.

For use in cats and small dogs only.

Recommended for hepatic support.

Directions for Use:
Cats: 2 capsules daily
Dogs: 1 capsule per 10 lbs body weight twice daily

Safe use in pregnant animals or animals intended for breeding has not been proven.

If animal's condition worsens or does not improve, stop product administration and consult your veterinarian.

May be GI irritant. Do not use in high doses with anticoagulant drugs or in patients with stomach ulcers.

For animal use only.

Keep out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately.

The Cautions and Warnings for individual Thorne Vet products are required to be included on the label by the National Animal Supplement Council (NASC) and were written by the NASC's Scientific Advisory Risk Assessment Committee

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Disclaimer: The statements enclosed herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease

Since we do not know everything about your medical history and medications, please consult with your health care practitioner before implementing any new protocols and supplements. Do not construe any information listed on this site as a substitute for actual medical advice. The info you receive from us is not intended to replace medical advice by your doctor. Forrest Health, Inc. does not dispense medical advice, prescribe, or diagnose illness. We offer nutritional programs and supplements that support your health. The views and nutritional advice expressed by Forrest Health, Inc. are not intended to be a substitute for conventional medical service. If you have a medical condition, see your physician of choice