DMSA Chelation Suppository - 25 count

DMSA Chelation Suppository - 25 count
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ZTL003
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25 Suppositories
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DRKR
MPN
LV15936
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859754004082
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$259.00
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$192.00
 
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DMSA Chelation Suppository - 25 count | Zetpil

DMSA is a sulfur-containing natural compound, in an advanced absorption enhancing proprietary, all natural base, designed to effectively and efficiently remove Organic and Inorganic mercury, and other metals from the body.*

 

  • DMSA is called a succimer, which means it has the chemical structure to combine with lead in the bloodstream and then it can be removed from the body by the kidneys.
  • The FDA has approved DMSA as front-line treatment for chelation of Organic and Inorganic mercury, lead, arsenic, cadmium, antimony, tin and tungsten.
  • Harmful heavy metals can accumulate in and thereby disrupt function in vital organs and glands such as the heart, brain, kidneys, bone, and liver.
  • Rectal suppository absorption rate is approximately 80-85%whereas oral DMSA only has a 20-25% absorption rate.*

 

  • The only extensively research based compound for the effective removal of four common toxic elements: Mercury, Lead, Cadmium and Arsenic.*
  • Little or no gastrointestinal side effects with the oral form of DMSA.*
  • More effective and significantly less costly than intravenous CaNa2EDTA*
  • Less side effects than the painful injectable mercury detox DMPS*
  • A safe detox that does not affect iron, calcium or magnesium levels*
  • An innovative proprietary all natural therapeutic suppository base in an easy to use, non-irritating, comfortable base*

DMSA is an organic compound that is FDA approved for the treatment of lead and mercury toxicity both in children and adults. Although it is sold as a prescription drug, it is also available as a dietary supplement. DMSA has been administered as a heavy metal detox since the 1950s, and no other substance has been found to be more practical, safer, and more effective for this purpose.*

Mercury contamination is most often associated with fish consumption, mercury amalgam dental fillings, mercury preservatives in vaccines, and other modern industrial exposures. Historically, lead contamination has been connected mainly to lead-based paints and leaded gasoline, both of which have been discontinued. However, children can still be exposed to old lead-based paint, and lead contamination is still an issue in areas where lead is being mined or smelted.*

Other heavy metals include cadmium and arsenic, which are derived mainly from cigarette smoke but also from occupational and environmental exposures.*

It has long been recognized that sulfur-containing compounds have the ability to detox heavy metals. Within the normal operation of the human body, there are natural sulfur-containing compounds which perform this service, and these include N-acetyl-Cysteine (NAC), R-Lipoic Acid, A-Lipoic acid, S-adenysl methionine (SAMe), and reduced glutathione (rGSH).*



Pharmacology*

  • DMSA mobilized lead mainly from soft tissue, especially blood, brain, kidney and liver. With respect to redistribution of mobilized lead to critical organs and magnitude of decline in soft tissue lead concentration, DMSA appears to be a safe and particularly effective detox and thus may be a viable alternative or choice in the presence of interindividual variability factor -that may require the use of that to CaNa2EDTA.” (Cory-Slechta)*
  • “DMSA-detoxes lead mainly reflects lead concentrations in blood, soft tissues, and possibly also trabecular bone.” (Gerhardsson)*
  • Urinary mercury excretion is significantly increased by DMSA administration. (Roels)*
  • DMSA acts as an antioxidant in vitro and lowers blood pressure in lab animals. (Khalil-Manesh)*
  • DMSA reverses (only) some of the lead-induced immunotoxicity” (Chen). However the use of an oral nutrient protocol given during the use of DMSA and post treatment protocol for the reactive oxidative stress has been developed to facilitate the recovery of the brain and organs from the chronic immunotoxic insult caused by long term heavy metal immunotoxicity*
  • DMSA administration stimulates arsenic excretion in the urine. (Maehashi)*
  • When DMSA is taken orally, ABOUT 20% IS ABSORBED, blood level peaks in 2-4 hours. Excretion is much slower, with a half-life of approximately 2 days. (Facts & Comparisons) DMSA is primarily excreted in the urine, mostly as DMSA-cysteine disulfide. (Aposhian).
  • Clinical experience indicated that a generally assumed absorption rate via rectal suppository, assuming an interindividual variability factor could be a conservative estimate of 75% absorption via the rectum.*
  • DMSA increases the excretion of ZINC AND COPPER. This requires an oral MV&M upon rising during the course of treatment.*
  • DMSA does not affect excretion of iron, calcium or magnesium. (Facts & Comparisons) as does EDTA (without Na and Ca)*



Heavy metal detoxification*

  • It is considered safe and effective in children at recommended doses.*
  • DMSA is labeled for use in children with blood lead concentrations in excess of 45 micrograms/dL.*
  • Evidence exists that DMSA is effective in lowering the blood lead concentrations in children with*  
  • Levels between 25 and 45 micrograms/dL.” (Berlin)*
  • DMSA is recommended as a single oral agent OR in combination with other detox agents, however it is recommended that you gain experience with the use of DMSA as a single agent before proceeding the use of a combination therapy. DMSA has been shown to be effective for the detoxification of a number of heavy metals, including mercury, lead, cadmium and arsenic.*
  • DMSA seems to be promising in the treatment of occupational lead poisoning.” (Peru)*
  • Detox therapy with DMSA in adults with moderate to severe lead poisoning is effective and safe. (Lifshitz)*
  • DMSA can be used in combination with EDTA detox therapy in the treatment of severe lead intoxication in children; it is recommended that any combination therapy be monitored closely. (Gordon)*
  • DMSA offers encouragement with regard to its therapeutic potential for pregnant women exposed to methyl mercury. (Sanchez)*

Zetpil™ Suppository Advantage

Zetpil™ delivers nutrition via the rectum with the use of suppositories that have a unique, all- natural formulated base that has revolutionized not only this mode of delivery, but also the ability to obtain nutrients in a far more efficacious method.  These suppositories are a result of combining natural ingredients with a non-irritating, rapid melting (5-6 minutes), readily absorbable (superior retention), antioxidant base material (free radical scavenging ability) and delivers the nutrients directly into the bloodstream in less than 20 minutes in a highly effective manner. Oral supplements are exposed to the hazards of stomach acid, digestive enzymes, food-related breakdown, first pass metabolism, and other bioavailability issues in the gastro-intestinal system.

Additionally, many raw materials simply have a very low bioavailability , and only achieve around 10% or less (commonly <1%) absorption rates, even if the patient is in optimal health condition. Compromised health, age, or certain conditions that result in an inability to take oral nutrients often preclude these patient populations from obtaining the necessary nutrition to stay healthy which often exacerbates chronic health issues.

Zetpil™ suppositories are a NOW solution to delivering the necessary nutrients to patients, on a daily basis, that is both easy, comfortable and cost effective. The safety and noticeable effectiveness of these products will far outweigh any initial hesitation you have regarding this mode of delivery.

The Zetpil™ DMSA Suppository Makes More Sense than Oral DMSA

Clinical experience has shown the rectal suppository absorption rate to be approximately 80-85% whereas oral DMSA only has a 20-25%absorption rate. www.who.int/…/4_2_LeadOralChelators.pdf  Additionally, there are essentially no side effects with suppository treatmentwhereas oral DMSA has demonstrated a high incidence of side effects including nausea, vomiting, diarrhea, appetite loss, hemorrhoidal symptoms, loose stools, metallic taste in mouth, back pain, abdominal cramps, stomach pains, gastritis, fever, flu-like symptoms, headache and Candida Albicans over-growths

DMSA Chelation Suppository - 25 count | Zetpil

This item is not returnable
 
Serving Size:  1 suppository

 

Servings per Container:  25

Each Zetpil™ DMSA TMD contains a proprietary blend of DMSA (2, 3 dimercaptosuccinic acid) 260mg, Taurine, and Arginine.  

 

**

Suppository Base: The base is a proprietary combination of excipients of plant and fruit butters, vegetable acids, medium chain triglycerides, phospholipids, lecithin, vegetable starches, cellulose, oligosaccharide derivatives and polysaccharide derivatives.

This product contains an extract from soybeans making it contraindicated in individuals with a known hypersensitivity to phospholipids, sesame seed oils or any of the listed ingredients.

If you choose to use this product as a rectal suppository, it is highly recommended you attempt to clear your bowels prior to inserting it to avoid premature evacuation.  To facilitate insertion it is recommended you moisten the product by passing it under a stream of cool water or use a personal lubricant. When used as a suppository, this product requires 15-20 minutes retention to ensure the complete absorption of the bioactive ingredients. This suppository can be inserted in any position. Although not required, if inserted while lying on one’s side, consider remaining in the supine position for 1-3 minutes following insertion. (Always insert flat end of suppository first).

If you desire to use this product as a suppository or a pessary and it becomes too soft to effectively insert into the rectum or vagina, place the product in the refrigerator for no longer than 10 minutes or until it becomes firm.

Note- this product loses potency when kept in temperatures below 59 degree Fahrenheit.

WARNINGS

  • Although safe for children, this product should be kept out of the reach of children.
  • Do not use if the suppositories are open or damaged.
  • As with any nutrient if you are pregnant or breastfeeding, seek the advice of a health care provider before using this product.

Individuals that have chosen to take this product as part of a personal nutrient program have overwhelmingly chosen to utilize this product as a rectal suppository or as a vaginal pessary.  However, this product can also be taken safely by mouth. If one chooses to take this product orally, then this product may be considered a dietary supplement in accordance with current FDA guidelines.

 

MONTHLY SCHEDULE for Safe and Effective DMSA Chelation Therapy

DAY 1 THROUGH DAY 5:
2 (two) 260mg Zetpil™ DMSA Suppositories before retiring
2 (two) Zetpil™ MV&MM Suppositories
1 Melatonin Suppository and 1 Reduced Glutathione Suppository

 


 

DAY 5 THROUGH DAY 20:
1 (one) 260mg Zetpil™ DMSA Suppositories before retiring
2 (two) Zetpil™ MV&MM Suppositories
1 Melatonin Suppository and 1 Reduced Glutathione Suppository

 


 

DAY 21 THROUGH DAY 30:
DO NOT USE THE Zetpil™ DMSA Suppository for 10 days
2 (two) Zetpil™ MV&MM Suppositories
1 Melatonin Suppository and 1 Reduced Glutathione Suppository

Disclaimer: These statements have not been evaluated by the FDA. This product is a Federal Food, Drug, and Cosmetic Act compliant combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals and amino acids products legally sold in the USA.  In accordance with FDA regulations, when taken orally, this product may be considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff).

Also, this product consists ONLY of a combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals and amino acids products legally sold in the USA. Therefore, this product cannot be considered a drug as defined in section 201(g)(1) of the Act, 21 U.S.C. § 321(g)(1). This product is not intended to affect the structure or function of the body and is not intended for use in the diagnosis, cure, mitigation, treatment or prevention of disease in man. Any nutritional suggestions and research regarding this product are provided for informational purposes only, and are not intended to diagnose, treat, cure or prevent disease nor should any information provided be used as a  substitute for sound medical advice

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Why Is the detox of Heavy Metals So Important? 
Mercury contamination is most often associated with fish consumption, mercury amalgam dental fillings, mercury preservatives in vaccines, and other modern industrial exposures. Historically, lead contamination has been connected mainly to lead-based paints and leaded gasoline, both of which have been discontinued. However, children can still be exposed to old lead-based paint, and lead contamination is still an issue in areas where lead is being mined or smelted. 

Other heavy metals include cadmium and arsenic, which are derived mainly from cigarette smoke but also from occupational and environmental exposures. 
  
It has long been recognized that sulfur-containing compounds have the ability to detox heavy metals. Within the normal operation of the human body, there are natural sulfur-containing compounds include N-acetyl-Cysteine (NAC), R-lipoic acid, S-adenysyl methionine (SAMe), and glutathione (GSH), however these compounds have proven to more of adjunctive compounds and less effective when significant heavy metal toxicity is present. 
 
The Zetpil™ DMSA Suppository is an Effective and Preferred Heavy Metal detox
Chemically, DMSA is a dithiol, which means that it contains two sulfhydryl (also know as S-H) groups.
  • Urinary mercury excretion is significantly increased by DMSA administration versus CaNa(2)EDTA. (Roels)
  • DMSA mobilized Lead mainly from soft tissue, especially blood, brain, kidney and liver. With respect to redistribution of mobilized lead to critical organs and magnitude of decline in soft tissue lead concentration, DMSA appears to be a safe and particularly effective detox and thus may be a viable alternative or choice where to CaNa(2)EDTA has proven irritating or less effective (Cory-Slechta)
  • DMSA-detox lead mainly reflects lead detox from lead concentrations in the  blood, soft tissues, and possibly also trabecular bone. (Gerhardsson)
  • detox therapy with DMSA in adults with moderate to severe lead poisoning is effective and safe. (Lifshitz)
  • Like CaNa(2)EDTA, DMSA reverses (only) some of the lead-induced immunotoxicity (Chen). Therefore the use of the adjunctive (additional) Zetpil™ oral antioxidant nutraceutical, nutrient protocol during the use of the Zetpil™ DMSA Suppository DMSA and post treatment protocol for the reactive oxidative stress and reactive nitrogen stress has been developed to facilitate the recovery of the brain and organs from the chronic immunotoxic insult caused by long term heavy metal immunotoxicity.
  • Evidence exists that DMSA is effective in lowering the blood lead concentrations in children with levels between 25 and 45 micrograms/dL.” (Berlin) and is considered safe and effective in children at recommended doses under the supervision of a qualified healthcare professional.
  • DMSA administration stimulates arsenic excretion in the urine. (Maehashi)
  • DMSA acts as an antioxidant in vitro and lowers blood pressure in lab animals. (Khalil-Manesh)
  • DMSA does not affect excretion of iron, calcium or magnesium. (Facts & Comparisons) However, DMSA may increase the excretion of zinc and copper. Therefore the use of the specially formulated Zetpil™ Oral Multivitamin and Mineral during the course of treatment with the Zetpil™ DMSA Suppository is recommended. 
  • The Zetpil™ DMSA Suppository is recommended as a single detox agent only. Although there has been some discussion and animal studies demonstrating the use of  DMSA and CaNa(2)EDTA, this combination has not been evaluated to any large extent in humans and accordingly is NOT RECOMMENDED.   
 
The Zetpil™ DMSA Suppository Makes More Sense than Oral DMSA
  • Clinical experience has shown an absorption rate via rectal suppository, to be approximately 70% absorption via the rectum whereas DMSA taken orally, is poorly absorbed (approximately 20%) with blood level peaks in 2-4 hours. Excretion is much slower, with a half-life of approximately 2 days. (Facts & Comparisons). The peak blood levels do not differ appreciably.
  • There are essentially no gastrointestinal side effects with the therapeutic dosage delivered via the Zetpil™ DMSA Suppository whereas oral DMSA has demonstrated a high incidence of gastrointestinal side effects including nausea, vomiting, diarrhea, appetite loss, hemorrhoidal symptoms, loose stools, metallic taste in mouth, back pain, abdominal cramps, stomach pains, gastritis, fever, flu-like symptoms, headache and Candida Albicans over growths.
 
The Zetpil™ DMSA Suppository is Very Safe!
 
DMSA has a large “therapeutic window”, meaning that there is a wide margin between the amount needed to produce desired results and the amount that is potentially toxic. The Zetpil™ DMSA Suppository greater absorbability allows for the use of a lower effective dosage as well as the virtual elimination of the many of the systemic and gastrointestinal side effects associated with oral DMSA.
 
 
Other Clinical Applications
Challenge test for heavy metal intoxication 
The Zetpil™ Provocation Protocol for Heavy Metal Urinalysis
 
Zetpil™ has created a 3 day provocation test that consists of a double dosage of The Zetpil™ CaNa(2)EDTA Suppository for evenings 1 and 2, and the Evidence exists that The Zetpil™ DMSA Suppository on the 3rd evening before collecting the next morning’s first and second urine. 

  • Disclaimer

*Your results may vary from those listed above.

*These statements have not been evaluated by the Food and Drug Administration.
*This product is not intended to diagnose, treat, cure or prevent any disease.

Since we do not know everything about your medical history and medications, please consult with your health care practitioner before implementing any new protocols and supplements. Do not construe any information listed on this site as a substitute for actual medical advice. The info you receive from us is not intended to replace medical advice by your doctor. Forrest Health, Inc. does not dispense medical advice, prescribe, or diagnose illness. We offer nutritional programs and supplements that support your health. The views and nutritional advice expressed by Forrest Health, Inc. are not intended to be a substitute for conventional medical service. If you have a medical condition, see your physician of choice.